- Vatican Safes: There are 7 primary safes to unlock in the Vatican area.
- Key Rewards: Safes contain Combat Skill Books, artifacts, and medicine maps.
- Dynamic Puzzles: Most codes are found by inspecting notes, ticket stubs, or environmental clues.
- Major Quests: Several safes are locked behind Fieldwork like A Nun in Trouble and Savage Discovery.
- Essential Code: The first safe in Belvedere Court uses the code 5238.
Unlocking the various secrets hidden within the Vatican requires a keen eye and a sharp mind, especially when it comes to finding all the Indiana Jones and the Great Circle safe codes. As Indy navigates the treacherous corridors and sun-drenched courtyards of the Holy See, he will encounter numerous locked safes containing invaluable skill books, artifacts, and wealth. These safes are often tied to specific Fieldwork quests or environmental puzzles that demand more than just brute force to solve. Whether you are hunting for the combat skill book in the Belvedere Court or trying to decipher the complex planetary alignment in the Sistine Chapel, knowing the correct combinations is essential for character progression. This comprehensive guide provides the exact solutions for every safe in the Vatican region, ensuring you never miss a piece of loot. By mastering the Indiana Jones and the Great Circle safe codes, you can focus on the action and adventure while staying ahead of your enemies in 2026.
Vatican Open World Safe Locations
The open-world section of the Vatican is the first major area where you will need to hunt for codes. These safes are often tucked away in tents or hidden cellars that require specific keys found on enemies or through exploration.
Video Highlights:
- Detailed walkthrough for all 7 Vatican safe locations.
- Visual guide for the Planetary Chart puzzle in the Sistine Chapel.
- Solutions for the Father and Son poem cipher.
- Location of the hidden Museum Basement safe.
The first safe you will encounter is located in the Belvedere Court. Upon reaching the open area, look for the first military tent directly in front of you. On the desk inside, you will find a ticket stub. By inspecting the front and back of the stub, you can piece together the four-digit code.
| Location | Clue Object | Safe Code | Reward |
|---|---|---|---|
| Belvedere Court Tent | Ticket Stub | 5238 | Combat Skill Book, Money |
| Post Office Cellar | Guard's Note | 1136 | Quest Progression, Loot |
The Belvedere Court is heavily patrolled. Ensure you clear the immediate guards or use stealth before attempting to inspect the ticket stub on the desk, as being spotted will interrupt the inspection animation.
Another critical location is the cellar beneath the post office, near the Tower of Nicholas. This is part of the Savage Discovery fieldwork. You must first obtain the Cellar Key from a nearby enemy. Once inside, take out the guard and read the note he carries. The note mentions "November last year." Since the game is set in 1937, "last year" refers to 1936, and November is the 11th month, giving you the code 1136.
Museum and Garden Puzzles
The A Nun in Trouble fieldwork leads you to some of the most rewarding safes in the game. These require a combination of calendar reading and environmental interaction.
Museum Garden Safe
Located in the tent at the back of the garden. Requires solving the Calendar Dice puzzle based on a delivery letter dated October 15th.
Museum Basement Safe
Found during the museum infiltration. This safe is unique because the code is hidden in plain sight using lighting.
To unlock the Garden safe, you must find the "Secret Delivery Letter" which states a package arrived on October 15th. By checking the in-game calendar, you see that October 15th falls on a Friday. Cross-referencing "Friday" with the dice symbols on the calendar reveals the code 6380. Inside, you will find a book detailing all medicine locations in the Vatican.
Locate the Basement Safe
Enter the museum basement during or after the "A Nun in Trouble" quest.
Interact with the Desk
Find the desk with the lamp next to the safe.
Turn Off the Light
Interact with the lamp to turn it off. The shadows/glow will reveal the code 7171 etched into the desk surface.
Even after completing the fieldwork, you can fast travel back to the Garden location to access the Museum Basement if you missed the safe during your initial run.
Sistine Chapel and Mystery Safes
The Sistine Chapel holds two distinct safes, both tied to "Mysteries" that offer some of the best narrative rewards and skill boosts in the game.
The Secret of Secrets mystery is triggered in the back office of the Sistine Chapel. You will find a note instructing you to inspect the statues of Peter (with the key) and Paul (with the sword). Turning these statues over reveals planetary symbols. You must then find the planetary chart in the room and order the planets by their distance from the sun.
| Planet Symbol | Order from Sun | Resulting Digit |
|---|---|---|
| Statue 1 Symbol | 4th Position | 4 |
| Statue 2 Symbol | 4th Position | 4 |
| Statue 3 Symbol | 7th Position | 7 |
| Statue 4 Symbol | 1st Position | 1 |
The final code for this complex puzzle is 4471. This unlocks a mystery book and an additional skill book. Later, after completing the nun's questline, you can return for Gina's Request (Signs of Trouble). This safe is located in a singular building at the excavation site. The code, 1891, is written clearly at the bottom of Gina's note.
Completing these safe-related mysteries contributes significantly to your overall completion percentage for the Vatican district.
The Father and Son Cipher
Perhaps the most intricate safe is tied to the Father and Son mystery. This safe is located near the Borgia Tower in a side room that requires Juliana's Key to enter. Inside, you will find a cat, a dog, and a cryptic poem.
To solve this, you must loot the poem and look at the circled letters: I, R, I, A, T, A, S, O. You then need to compare these letters to a square diagram found in the room. Each letter or combination of letters corresponds to a specific number on the grid.
| Letter Group | Grid Coordinate | Resulting Digit |
|---|---|---|
| I / R | Row 5 | 5 |
| I / A | Row 8 | 8 |
| T / A | Row 7 | 7 |
| S / O | Row 3 | 3 |
Following the sequence of the poem's circled letters leads to the code 5873. Unlocking this safe concludes the Father and Son mystery, providing a significant boost to your adventure points.
Once you input 5873, the safe will open, rewarding you with unique lore items and finishing one of the most difficult puzzles in the Vatican.
Vatican Safe Checklist
Use this checklist to ensure you have collected every reward from the Vatican safes in 2026.
Safe Completion Tracker:
- Belvedere Court (Code: 5238) - Combat Skill Book
- Sistine Chapel Office (Code: 4471) - Secret of Secrets
- Post Office Cellar (Code: 1136) - Savage Discovery
- Museum Garden (Code: 6380) - Medicine Map
- Museum Basement (Code: 7171) - Rare Artifact
- Borgia Tower Room (Code: 5873) - Father and Son
- Excavation Site Building (Code: 1891) - Signs of Trouble
Frequently Asked Questions
Q: Where do I find the Indiana Jones and the Great Circle safe codes for the Vatican?
The codes are found through environmental clues like ticket stubs (5238), guard notes (1136), or by solving puzzles like the planetary chart (4471) and the poem cipher (5873).
Q: What is the code for the safe in the museum garden?
The code is 6380. It is derived from the delivery date of October 15th, which is a Friday on the in-game calendar, corresponding to specific dice symbols.
Q: How do I get the code for the museum basement safe?
You must turn off the desk lamp next to the safe. This reveals the number 7171 written on the desk surface.
Q: Are the safe codes the same in every playthrough?
Yes, the safe codes in Indiana Jones and the Great Circle are static and do not change between different save files or difficulty settings.